Temperature-dependent sex determination is a notable model of phenotypic plasticity. In many reptiles, including the red-eared slider turtle Trachemys scripta elegans T. KDM6B directly promotes the transcription of the male sex-determining gene Dmrt1 by eliminating the trimethylation of H3K27 near its promoter. Additionally, overexpression of Dmrt1 is sufficient drake snapchat username rescue the sex reversal induced by disruption of Kdm6b This study establishes causality and a direct genetic hypno doms between epigenetic mechanisms and temperature-dependent sex determination in a turtle species.
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Comment in How does temperature determine sex? Georges A, Holleley CE. Georges A, et al.
PMID: No abstract available. Some like it hot - sex determination in turtles.
Koch L. Nat Rev Genet. An epigenetic regulatory switch controlling temperature-dependent sex determination in vertebrates. Li XY, et al. Sci China Life Sci. Epub Jun Weber C, et al. PMID: Dmrt1 induces the male pathway sext a turtle species with temperature-dependent sex determination.
Ge C, et al. Epub May Expression of Dmrt1 in a turtle with temperature-dependent sex determination. Murdock C, Shibari positions T. Murdock C, et al. Cytogenet Genome Res. Molecular mechanisms of temperature-dependent sex determination in the context of ecological developmental biology. Matsumoto Y, Crews D. Matsumoto Y, et al. Mol Cell Endocrinol. Epub Oct PMID: Review. Temperature-dependent sex determination in the red-eared slider turtle, Trachemys scripta.
Wibbels T, snapchat hoes to add al. J Exp Zool.
The histone demethylase kdm6b regulates temperature-dependent sex determination in a turtle species
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Publication types Research Support, Non-U. Gov't Actions.
MeSH terms Animals Actions. DNA Methylation Actions. Female Actions. Gene Expression Regulation, Developmental Actions. Gene Knockdown Techniques Actions.